Sunday, May 10, 2020
Sunday, May 10, 2020 8:00 am – 11:30 am Kalakaua Ballroom B
Major Symposium C: An Immunological Angle on the Brain and its Diseases
- Jonathan Kipnis, Univ. of Virginia
- Zsuzsanna Fabry, Univ. of Wisconsin, Madison
- Zsuzsanna Fabry, Univ. of Wisconsin, Madison, Dendritic cells link neuroinflammation and lymphangiogenesis in the brain
- Jonathan Kipnis, Univ. of Virginia, Meningeal immunity and lymphatics in the brain’s immune surveillance
- Jenny P. Ting, Univ. of North Carolina, Chapel Hill Sch. of Med., Crossing over of innate immune receptors to adaptive immunity and implications in neuroinflammation
- Antoine Louveau, Lerner Res. Inst., Regulation of brain maturation by the meningeal lymphatic vasculature
- Isaac Chiu, Harvard Univ., Neuronal detection of bacterial pathogens and regulation of immunity
- Ashley Moseman, Duke Univ. Sch. of Med., Coordinating CNS host defense following olfactory neuroinvasion
Sunday, May 10, 2020 8:00 am – 11:30 am Kalakaua Ballroom C
Major Symposium D: Innate Immunity: The Good, The Bad, The Ugly
- Clara Abraham, Yale Univ.
- Katherine Fitzgerald, Univ. of Massachusetts Med. Sch.
- Clara Abraham, Yale Univ., Modulation of innate immune responses by disease-associated genes
- Katherine Fitzgerald, Univ. of Massachusetts Med. Sch., Regulation of inflammation by nucleic acid binding proteins
- Kodi S. Ravichandran, Univ. of Virginia, Soothing messages on the way out: apoptotic cell communication with the neighborhood
- Daniel Stetson, Univ. of Washington, Innate immune detection of intracellular DNA
- Raphaela Goldbach-Mansky, NIAID, NIH, Innate immune dysregulation in autoinflammatory diseases
- Gregory Sonnenberg, Weill Cornell Med. Col., Immune regulation of intestinal health
Sunday, May 10, 2020 8:00 am – 10:00 am Room 313B
American Society of Tropical Medicine and Hygiene (ASTMH) Symposium: Immune Lessons from Parasites
- Christine Petersen, Univ. of Iowa
- Keke Fairfax, Univ. of Utah Sch. of Med.
- Jude Uzonna, Univ. of Manitoba, Natural Killer cells contribute to optimal immunity against an extracellular protozoan parasite
- David Artis, Weill Cornell Med., Regulation of immunity and inflammation at mucosal tissue sites
- Pedro Gazzinelli-Guimaraes, NIAID, NIH, Pulmonary allergen-driven CD30L+Th2 effector cells promote an IL-5/IL-13 mediated eosinophil-dependent protective immunity against helminth larval stages in the lungs
- Camila Coelho, NIAID, NIH, A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes
Sunday, May 10, 2020 8:00 am – 10:00 am Room 315
National Institute on Aging (NIA) Symposium: Mucosal Immunity, Microbiome, and Aging
- Elizabeth Kovacs, Univ. of Colorado, Denver
- Charles R. Wira, Dartmouth Univ., Impact of aging on mucosal immune protection in the human female reproductive tract
- Dawn Bowdish, McMaster Univ., Canada, Does immunosenescence alter the upper respiratory tract microbiome and increase susceptibility to infection?
- Arya Biragyn, NIA, NIH, The cause and consequence of gut leakiness in aging
- Elizabeth Kovacs, Univ. of Colorado, Denver, Advanced age, injury and the gut-lung axis
Sunday, May 10, 2020 10:15 am – 11:15 am Room 317AB
Interviewing for a Job
- Derek Haseltine, Director, Career Develop. Ctr., Baylor Col. of Med.
This session will be focused on tips and techniques to help you successfully navigate the interview process. Emphasis will be on how you can present yourself in the best possible light. You will also learn how to respond to unexpected questions. This session is open to anyone but is especially intended for student and postdoctoral attendees.
Sunday, May 10, 2020 10:15 am – 11:45 am Room 313B
International Opportunities in Science
- Hanne Ostergaard, Univ. of Alberta, Canada
- Haiyan Liu, National Univ. of Singapore, Singapore
- Rune Hartmann, Aarhus Univ., Denmark
- Paula Longhi, Queen Mary University of London, United Kingdom
Working as a scientist outside of the U.S. requires curiosity, adaptability, and open-mindedness, which are valuable qualities important for success in any career. Given the international reach of science, this new session will help immunologists learn about opportunities to gain professional experience beyond the U.S. This panel features scientists employed at academic or research institutions around the globe. Panelists will discuss the postdoctoral fellowship and grant application process, the benefits of international training and employment, and the challenges in finding science-related jobs outside of the U.S. This session is open to anyone.
Sunday, May 10, 2020 10:15 am – 12:15 pm Room 314
Australasian and New Zealand Society for Immunology (ASI) Symposium: B Cells Down Under
- Ian Parish, Peter MacCallum Cancer Ctr., Australia
- Sammy Bedoui, Peter Doherty Inst. for Infection and Immunity, Australia
- David Tarlinton, Monash Univ., Australia, The development and population dynamics of long-lived antibody secreting cells
- Elissa Deenick, Garvan Inst. of Med. Res., Australia, Critical signaling pathways controlling protective B cell responses revealed by inborn errors of immunity
- Phil Hodgkin, Walter and Eliza Hall Inst. of Med. Res., Australia, The mechanics of B cell signal integration in health and disease
- Kim Good-Jacobson, Monash Univ., Australia, Regulation of antibody-mediated responses and immune memory formation by histone-modifying complexes during acute versus chronic viral infection
Sunday, May 10, 2020 10:15 am – 12:15 pm Room 315
Society for Immunotherapy of Cancer (SITC) Symposium: Understanding the T Cell Repertoire within the Cancer Microenvironment
- Andrew Weinberg, Earle A. Chiles Res. Inst., Providence Cancer Ctr.
- Drew M. Pardoll, Johns Hopkins Univ.
- Andrew Weinberg, Earle A. Chiles Res. Inst., Providence Cancer Ctr., Identifying tumor-reactive CD8+ tumor-infiltrating lymphocytes in patients with solid malignancies: clinical implications
- Alena Gros, Vall d’Hebron Inst. of Oncology, Spain, Harnessing the personalized antitumor T cell response to treat cancer
- Kathryn Yost, Stanford Univ., Clonal dynamics of tumor-infiltrating T cells in response to checkpoint blockade immunotherapy
- Drew M. Pardoll, Johns Hopkins Univ., Single-cell analysis of the PD1 responders versus the non-responders in the tumor microenvironment
Sunday, May 10, 2020 10:15 am – 12:15 pm Room 316B
Communicating about Vaccines to a Concerned and Uncertain Public
SPONSORED BY THE AAI Committee on Public Affairs
The World Health Organization named “vaccine hesitancy,” defined as “the reluctance or refusal to vaccinate despite the availability of vaccines,” one of the top ten threats to global health in 2019. Fueled in many instances by misinformation, people may become concerned or uncertain about the safety or efficacy of vaccines and may choose not to follow recommended vaccination guidelines for themselves or their children. This can have devastating consequences, including the resurgence of vaccine-preventable diseases, as evidenced by last year’s measles outbreak, the largest reported in the United States in over 25 years. Given the serious risk to global health posed by vaccine hesitancy, it is crucial for immunologists to understand and be able to address public concerns. This session will feature expert speakers who will discuss the rise in vaccine hesitancy, describe how the problem is currently being addressed, explain how scientists can effectively communicate about vaccines to the public, and answer audience questions.
Sunday, May 10, 2020 12:30 pm – 2:30 pm Room 313B
American Society of Transplantation (AST) Symposium: Immune Tolerance: New Mechanisms and Barriers
- David Rothstein, Univ. of Pittsburgh
- Anita Chong, Univ. of Chicago
- Wenhao Chen, Houston Methodist Hosp. and Weill Cornell Med., IRF4, CD4+T cell dysfunction, and allograft acceptance
- Bernhard Hering, Univ. of Minnesota, Apoptotic cells for islet tolerance
- Anna Valujskikh, Cleveland Clin., Reshaping T cell memory by lymphoablation
- Mark Davis, Stanford Univ., Tolerogenic CD8+ T cells
Sunday, May 10, 2020 12:30 pm – 2:30 pm Room 316B
Canadian Society for Immunology (CSI) Symposium: The Bone and Sinew of the Cell: Cytoskeletal Processes in Immunity
- Judith Mandl, McGill Univ., Canada
- Michael Gold, Univ. of British Columbia, Canada
- Judith Mandl, McGill Univ., Canada, From cell migration to T cell responses: what could go wrong!
- Thomas Murooka, Univ. of Manitoba, Canada, Altered migration and cell-cell contact dynamics during viral infection
- Emily Mace, Columbia Univ., New insights into human NK cell migration
- Spencer Freeman, Hosp. for Sick Children, Canada, Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance
- Michael Gold, Univ. of British Columbia, Canada, Regulation of B cell function by actin-regulatory proteins
Sunday, May 10, 2020 12:30 pm – 2:00 pm Kalakaua Ballroom A
Careers in Science Roundtable
Sponsored by the AAI Education Committee & AAI Committee on the Status of Women
- Laura A. Solt, Scripps Res.; AAI Committee on the Status of Women Chair
- Joan Goverman, Univ. of Washington, Overcoming self-doubt and becoming a confident scientist
At this popular session, attendees will have the opportunity to meet with experienced scientists to explore specific career issues important to men and women in science today. Gain insights into issues you are confronting in your own career. Topics include international opportunities in science, succeeding in graduate school, tips on grant writing, considerations for scientists in M.D.-Ph.D. careers, and exciting careers beyond the bench. New to the 2020 session are topics on building productive mentor/mentee relationships, overcoming self-doubt, and tackling gender biases in recruitment, research, and leadership. There are also table discussions on navigating work-life issues, such as balancing careers with family and transitioning from specific career stages, which may be relevant to any work environment (academic research, biotech industry, governmental agencies, non-profit). Don’t miss this great networking opportunity!
Registration Fee: $30 (lunch included)
Discussion topics and table leaders:
Research Careers in Academia
- Succeeding in Graduate School
Steven Templeton, Indiana Univ. Sch. of Med.; Bao Q. Vuong, The City Col. of New York
- Graduate Student to Postdoc: finding a postdoc, interviewing
Ann Griffith, Univ. of Texas Hlth. San Antonio; Lyse A. Norian, Univ. of Alabama, Birmingham; Irene Salinas, Univ. of New Mexico
- Postdoc to PI
- Government Research Institutions
- Medical Schools
Andre Ballesteros-Tato, Univ. of Alabama, Birmingham; Lisa K. Denzin, Child Hlth. Inst. of New Jersey
- Government Research Institutions
- New PI (mentoring effectively, recruiting students and postdocs, preparing for promotion, tips for balancing teaching and research):
Martin J. Richer, McGill Univ.; Matthew R. Olson, Purdue Univ.
- Building Networking Skills
Laura A. Solt, Scripps Res.
Building Productive Mentor/Mentee Relationships
- Louis B. Justement, Univ. of Alabama, Birmingham
Overcoming Self-Doubt and Becoming a Confident Scientist
- Tina L. Sumpter, Univ. of Pittsburgh; Joan Goverman, Univ. of Washington
Tackling Gender Biases in Recruitment, Research, and Leadership
- Virginia Shapiro, Mayo ClinicCareers in Veterinary Immunology
Careers in Veterinary Immunology
- Mercedes Gonzalez-Juarrero, Colorado State Univ.; Crystal L. Loving, USDA
Work / Life Balance
- Elizabeth A. Leadbetter, Univ. of Texas Hlth. San Antonio; Andrea Sant, Univ. of Rochester
Careers in Biotech and Industry: moving from academia to industry and vice versa
- Markus Mohrs, Regeneron Pharmaceuticals; Kritika Ramani, Evelo Biosciences; David J. DiLillo, Regeneron Pharmaceuticals; Stephen T. Haley, Immudex; Sadiye Rieder, Viela Bio; Ira Mellman, Genentech
Careers at Governmental Agencies
- Konrad Krzewski, NIAID, NIH; Deborah Hodge, CSR, NIH
NIH Study Section Insights
- Grant Writing for Fellowships/Transition Awards
Melissa A. Brown, Northwestern Univ. Feinberg Sch. of Med.
- Grant Writing for PIs
Meera G. Nair, Univ. of California, Riverside
The Physician Scientist: balancing clinical and research duties
- Penelope A. Morel, Univ. of Pittsburgh; Maureen A. Su, Univ. of California, Los Angeles
Research from the M.D., Ph.D. Perspective
- Xunrong Luo, Duke Univ. Sch. of Med.; Liza Konnikova, Univ. of Pittsburgh
Non-Research Careers for Scientists: careers enabling scientists to advance the field away from the bench
- Scientific Publishing
Ellen C. Fox, The Journal of Immunology, AAI
- Opportunities for Scientists in Foundations/Non-profits
Courtney R. Pinard, Career Development and Awards, AAI
- Careers in Science Policy
Lauren G. Gross, Public Policy and Government Affairs, AAI; Lauren L. Brodd, Public Policy and Government Affairs, AAI
International Opportunities in Science
- Hanne Ostergaard, Univ. of Alberta
- Winfried F. Pickl, Medical Univ. of Vienna
Sunday, May 10, 2020 12:30 pm – 2:30 pm Room 314
How to Write a Scientific Paper, Respond to Reviews, and Disseminate Your Findings
Sponsored by the AAI Publications Committee
- Tania H. Watts, Univ. of Toronto, Canada; AAI Publications Committee Chair
- Eugene M. Oltz, Ohio State Univ. Coll. of Med.; Editor-in-Chief, The Journal of Immunology
- Tania H. Watts, Univ. of Toronto, Canada, What’s your punchline? How to write a compelling manuscript
- Gail A. Bishop, Univ. of Iowa, What to do when reviews arrive
- Akiko Iwasaki, Yale Univ., How to use Twitter to promote your publication
- Eugene M. Oltz, Ohio State Univ. Coll. of Med., Why you should publish in The JI – and ImmunoHorizons too!
In this session sponsored by the AAI Publications Committee, experienced editors and authors will provide valuable insights to the processes of preparing a manuscript, responding to reviewers’ comments, and how to use social media to spread the word about your work. In addition, the Editor-In-Chief of The Journal of Immunology will speak on the career benefits of publishing in The JI.
Sunday, May 10, 2020 12:30 pm – 1:30 pm Room 316A
AAI-BioLegend Herzenberg Award Presentation and Lecture
Generously supported by BioLegend
- Jeremy M. Boss, Emory Univ. Sch. of Med., AAI President
Susan K. Pierce
Regulators and influencers of B cell affinity discrimination
AAI President Jeremy M. Boss and a representative from BioLegend will introduce the awardee and present the award immediately prior to Dr. Pierce’s lecture.
The AAI-BioLegend Herzenberg Award recognizes outstanding research contributions to the field of immunology in the area of B cell biology.
Sunday, May 10, 2020 3:45 pm – 5:45 pm Room 313B
Chinese Society for Immunology (CSI) Symposium: Long Noncoding RNA and cGAS Regulation of Immune Response
- Bing Sun, Chinese Acad. of Sci., China
- Rachel Caspi, NEI, NIH
- Yuting Ma, Chinese Acad. of Med. Sci. and Peking Union Med. Col., China, Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity
- Erwei Song, Sun Yat-sen Univ., China, NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death
- Mian Wu, Univ. of Sci. and Technol. of China, China, The lncRNA Neat1 promotes activation of inflammasomes in macrophages
- Tao Li, Inst. of Basic Med. Sci., Natl. Ctr. of Biomed. Analysis, China, Acetylation blocks cGAS activity and inhibits self-DNA-induced autoimmunity
- Bao Xue Ge, Tongji Univ. Sch. of Med., China, Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Sunday, May 10, 2020 3:45 pm – 5:45 pm Room 323C
The Obesity Society (TOS) Symposium: Adipocyte Crosstalk with Immune Cell Subsets in Obesity Drives Progression of Comorbid Diseases
- Valentina Perissi, Boston Univ.
- Gerald Denis, Boston Univ.
- Mi-Jeong Lee, Univ. of Hawaii, Resistance to glucocorticoid suppression of TGFβ contributes to impaired adipogenesis and fibrosis in human visceral omental depot
- Willa Hsueh, Ohio State Univ., The adipocyte functions as an immune cell
- Jason Whitmire, Univ. of North Carolina, Chapel Hill, Obesity-associated viral pathogenesis in mice
- Maria Paula Longhi, William Harvey Res. Inst., Univ. of London, Dendritic cells and adipose tissue
Sunday, May 10, 2020 4:30 pm – 5:30 pm Kalakaua Ballroom BC
AAI-Thermo Fisher Meritorious Career Award Presentation and Lecture
Generously supported by Thermo Fisher Scientific
- Jeremy M. Boss, Emory Univ. Sch. of Med., AAI President
Alexander Y. Rudensky
HHMI, Memorial Sloan Kettering Cancer Ctr., Rockefeller Univ., and Cornell Univ.
The virtue of restraint in adaptive immunity
AAI President Jeremy M. Boss and a representative from Thermo Fisher Scientific will introduce the awardee and present the award immediately prior to Dr. Rudensky’s lecture.
The AAI-Thermo Fisher Meritorious Career Award recognizes a mid-career scientist for outstanding research contributions to the field of immunology.
Sunday, May 10, 2020 6:00 pm – 6:45 pm Kalakaua Ballroom BC
Distinguished Lecture—Michael P. Cancro: A tale of two subsets: rethinking B cell selection, homeostasis, and memory
Michael P. Cancro
Perelman Sch. of Med., Univ. of Pennsylvania
A tale of two subsets: rethinking B cell selection, homeostasis, and memory
Sunday, May 10, 2020 7:45 pm – 10:00 pm Alohilani Hotel, Swell Lounge
Service Appreciation Reception (By Invitation Only)
Generously sponsored by BioLegend
AAI honors the dedicated member volunteers of the association—committee members, editors, abstract programming chairs, and others—who work on the membership’s behalf throughout the year by giving generously of their time in support of the AAI mission. Open (by invitation only) to 2019–2020 AAI volunteers.
(Badge and invitation required)